Ovarian and breast cancers are two of the most prevalent cancers in women—each affecting different organs, yet closely linked by genetics. Behind this link lies a powerful factor: mutations in the BRCA1 and BRCA2 genes.

According to the American Cancer Society, women diagnosed with breast cancer face twice the risk of developing ovarian cancer compared to the general population. This connection stems largely from inherited mutations that increase vulnerability to both diseases.

What the Research Reveals

• BRCA1 mutation carriers face up to a 72% lifetime risk of breast cancer and as much as a 44% risk of ovarian cancer.

• BRCA2 mutation carriers see slightly lower but still significant risks—69% for breast cancer and 17% for ovarian cancer.

These genetic mutations can be passed down from either parent, meaning a family history of either breast or ovarian cancer is a red flag—even if no relative has had both types.

Why Genetic Testing Matters

For women with a strong family history of these cancers, genetic testing can offer life-saving insight. Knowing your BRCA status allows you and your healthcare provider to create a personalized plan for early detection and prevention.

In families with multiple cases of breast or ovarian cancer, testing can help clarify the risks not only for you, but for future generations as well.

Other Shared Risk Factors

Beyond genetics, ovarian and breast cancer share other common risk factors:

• Advancing age

• Obesity

• Never having children

• Long-term hormone replacement therapy after menopause

Taking Control of Your Health

For high-risk individuals, preventive surgeries such as mastectomy (removal of breast tissue) or oophorectomy (removal of ovaries and fallopian tubes) may be considered to significantly lower cancer risk.

Ultimately, early awareness, genetic understanding, and proactive medical care are key to reducing your chances of developing these life-threatening diseases. With the right tools and information, women can take control of their health and make empowered decisions for a safer future.